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Laboratory particle counter for aqueous fluids with precise flow control for contamination monitoring, size distribution analysis and component cleanliness control

The system PAMAS SVSS is a standard laboratory particle counter for pharmaceutical applications (control of parenterals, infusion solutions, ophtalmic & oral fluids) and other low-viscous liquids. The instrument may be used as “stand alone” or software controlled.

A stepper-motor-actuated precision syringe moves the sample through the laser-diode sensor at the optimum flow-rate and an accurate sample volume is achieved. Using interchangeable syringes, the PAMAS SVSS can analyse sampling volumes of different sizes, from 100 µl to 1000 ml. For small volumes, a special “Small Volume Kit” is available.

The system can be used with different light extinction sensors. The standard sensor PAMAS HCB-LD-50/50 is equipped with a flow-rate of 10 ml/min and a size range of 1 to 200 µm.


  • Parenterals according to common pharmacopoeias
  • Water
  • Suspensions
  • Cleaning solvents

Product features

  • Customisable measurement settings
  • 16 freely adjustable
  • size channels (32 channels upon request)
  • Integrated magnetic stirrer
  • Use of any sample vessel
  • Measuring volume of 100 µl to 1000 ml
  • Automatic sample flow and volume control via a stepper motor driven syringe module
  • Interchangeable syringes with 1 ml, 10 ml and 25 ml volume

Standards and methods

ISO 21501-3 ISO 21501-2 USP <1788> ASTM D7647 USP <787>** USP <788>**
USP <789>** Ph. Eur. 2.9.19** JP XVI** KP X** IP 2.5.8** BP XIII**
ISO 11500          

**in connection with PAMAS USP software

Volumetric sensors

Available size ranges:
1–200 µm (ISO 21501-3)
1–400 µm (ISO 21501-3) option on request  
Max. particle concentration: 24,000 p/ml at 10 ml/min

Available size ranges:
1–200 µm (ISO 21501-3)
Max. particle concentration: 120,000 p/ml at 10 ml/min

Available size ranges:
0.5–20 µm (ISO 21501-2)
Max. particle concentration: 13,000 p/ml at 10 ml/min


PAMAS USP for pharmaceutical applications (compliant with 21 CFR Part 11)
PAMAS PMA for contamination control of clean liquids



PAMAS Partikelmess- und Analysesysteme GmbH
Dieselstraße 10
D-71277 Rutesheim / Deutschland

Phone +49 7152 9963-0
Fax +49 7152 9963-32
E-Mail info@pamas.de